| ECC Matches |
| |  | | | |
| 10 Aug 2010: Round 1, Leg 1
|
| Celtic | | 1 - 1 | | KRC Genk |
| Chievo | | 1 - 1 | | Villarreal |
| Everton | | 1 - 1 | | Legia Warsaw |
| FC Kobenhavn | | 1 - 4 | | Watford |
| FC Schalke 04 | | 2 - 2 | | Benfica |
| Nantes | | 0 - 5 | | Feyenoord |
| Osasuna | | 0 - 3 | | Inter |
| SK Rapid Wien | | 0 - 3 | | FC Basel 1893 |
| | | | | |
| 17 Aug 2010: Round 1, Leg 2
|
| Benfica | | 0 - 3 | | FC Schalke 04 |
| | (2 - 5 agg.) | |
| FC Basel 1893 | | 0 - 1 | | SK Rapid Wien |
| | (3 - 1 agg.) | |
| Feyenoord | | 1 - 1 | | Nantes |
| | (6 - 1 agg.) | |
| Inter | | 1 - 0 | | Osasuna |
| | (4 - 0 agg.) | |
| KRC Genk | | 2 - 1 | | Celtic |
| | (3 - 2 agg.) | |
| Legia Warsaw | | 0 - 1 | | Everton |
| | (1 - 2 agg.) | |
| Villarreal | | 0 - 1 | | Chievo |
| | (1 - 2 agg.) | |
| Watford | | 0 - 0 | | FC Kobenhavn |
| | (4 - 1 agg.) | |
| | | | | |
| 21 Sep 2010: Round 2 (Group Stage)
|
| Ajax | | 1 - 1 | | Galatasaray |
| Anderlecht | | 2 - 0 | | AC Sparta Praha |
| Bayern Munich | | 1 - 6 | | Wycombe |
| Brondby IF | | 0 - 4 | | Feyenoord |
| Chelsea | | 3 - 0 | | FC Basel 1893 |
| Everton | | 0 - 2 | | Barcelona |
| FC Schalke 04 | | 2 - 1 | | AC Milan |
| Inter | | 3 - 2 | | Fenerbahce SK |
| KRC Genk | | 1 - 1 | | Lyon |
| PSV Eindhoven | | 3 - 1 | | F.C. Porto |
| Palermo | | 0 - 1 | | AS Monaco |
| R. Madrid | | 1 - 1 | | Red Bull Salzburg |
| Valerenga | | 0 - 2 | | Sporting Lisbon |
| W. Bremen | | 2 - 1 | | Malmo FF |
| Watford | | 1 - 0 | | Olympiakos |
| Wisla Krakow | | 1 - 1 | | Chievo |
| | | | | |
| 28 Sep 2010: Round 2 (Group Stage)
|
| AC Sparta Praha | | 1 - 1 | | Wisla Krakow |
| AS Monaco | | 0 - 1 | | Barcelona |
| Brondby IF | | 0 - 1 | | Valerenga |
| Chievo | | 2 - 2 | | Anderlecht |
| Everton | | 1 - 0 | | Palermo |
| F.C. Porto | | 0 - 0 | | Chelsea |
| FC Basel 1893 | | 2 - 3 | | PSV Eindhoven |
| FC Schalke 04 | | 4 - 2 | | Ajax |
| Feyenoord | | 4 - 0 | | Sporting Lisbon |
| Galatasaray | | 0 - 0 | | AC Milan |
| Inter | | 1 - 1 | | Bayern Munich |
| Lyon | | 2 - 1 | | R. Madrid |
| Olympiakos | | 1 - 0 | | Malmo FF |
| Red Bull Salzburg | | 1 - 3 | | KRC Genk |
| Watford | | 2 - 0 | | W. Bremen |
| Wycombe | | 4 - 2 | | Fenerbahce SK |
| | | | | |
| 27 Oct 2010: Round 2 (Group Stage)
|
| AC Milan | | 0 - 2 | | Ajax |
| AS Monaco | | 3 - 2 | | Everton |
| Anderlecht | | 3 - 0 | | Wisla Krakow |
| Barcelona | | 1 - 0 | | Palermo |
| Chievo | | 1 - 1 | | AC Sparta Praha |
| FC Basel 1893 | | 3 - 1 | | F.C. Porto |
| Fenerbahce SK | | 2 - 0 | | Bayern Munich |
| Galatasaray | | 0 - 3 | | FC Schalke 04 |
| Lyon | | 2 - 2 | | Red Bull Salzburg |
| Malmo FF | | 0 - 4 | | Watford |
| PSV Eindhoven | | 1 - 0 | | Chelsea |
| R. Madrid | | 2 - 0 | | KRC Genk |
| Sporting Lisbon | | 0 - 1 | | Brondby IF |
| Valerenga | | 1 - 3 | | Feyenoord |
| W. Bremen | | 1 - 2 | | Olympiakos |
| Wycombe | | 4 - 1 | | Inter |
| | | | | |
| 2 Nov 2010: Round 2 (Group Stage)
|
| AC Milan | | 0 - 0 | | FC Schalke 04 |
| AC Sparta Praha | | 0 - 1 | | Anderlecht |
| AS Monaco | | 1 - 1 | | Palermo |
| Barcelona | | 0 - 1 | | Everton |
| Chievo | | 2 - 1 | | Wisla Krakow |
| F.C. Porto | | 3 - 1 | | PSV Eindhoven |
| FC Basel 1893 | | 0 - 2 | | Chelsea |
| Fenerbahce SK | | 1 - 0 | | Inter |
| Feyenoord | | 1 - 0 | | Brondby IF |
| Galatasaray | | 0 - 4 | | Ajax |
| Lyon | | 0 - 0 | | KRC Genk |
| Malmo FF | | 1 - 0 | | W. Bremen |
| Olympiakos | | 1 - 0 | | Watford |
| Red Bull Salzburg | | 0 - 1 | | R. Madrid |
| Sporting Lisbon | | 1 - 0 | | Valerenga |
| | | | | |
| 9 Nov 2010: Round 2 (Group Stage)
|
| AC Milan | | 2 - 1 | | Galatasaray |
| Ajax | | 0 - 2 | | FC Schalke 04 |
| Anderlecht | | 1 - 1 | | Chievo |
| Barcelona | | 0 - 1 | | AS Monaco |
| Bayern Munich | | 1 - 2 | | Fenerbahce SK |
| Chelsea | | 2 - 2 | | F.C. Porto |
| Inter | | 1 - 4 | | Wycombe |
| KRC Genk | | 3 - 1 | | Red Bull Salzburg |
| Malmo FF | | 0 - 5 | | Olympiakos |
| PSV Eindhoven | | 2 - 1 | | FC Basel 1893 |
| Palermo | | 0 - 1 | | Everton |
| R. Madrid | | 2 - 0 | | Lyon |
| Sporting Lisbon | | 1 - 0 | | Feyenoord |
| Valerenga | | 3 - 0 | | Brondby IF |
| W. Bremen | | 0 - 1 | | Watford |
| Wisla Krakow | | 1 - 1 | | AC Sparta Praha |
| | | | | |
| 1 Dec 2010: Round 2 (Group Stage)
|
| Bayern Munich | | 2 - 2 | | Inter |
| Fenerbahce SK | | 0 - 1 | | Wycombe |
| | | | | |
| 8 Dec 2010: Round 2 (Group Stage)
|
| AC Sparta Praha | | 2 - 2 | | Chievo |
| Ajax | | 1 - 2 | | AC Milan |
| Brondby IF | | 1 - 4 | | Sporting Lisbon |
| Chelsea | | 1 - 2 | | PSV Eindhoven |
| Everton | | 0 - 0 | | AS Monaco |
| F.C. Porto | | 0 - 1 | | FC Basel 1893 |
| FC Schalke 04 | | 1 - 0 | | Galatasaray |
| Feyenoord | | 3 - 1 | | Valerenga |
| KRC Genk | | 1 - 2 | | R. Madrid |
| Olympiakos | | 3 - 3 | | W. Bremen |
| Palermo | | 0 - 1 | | Barcelona |
| Red Bull Salzburg | | 0 - 1 | | Lyon |
| Watford | | 3 - 0 | | Malmo FF |
| Wisla Krakow | | 1 - 3 | | Anderlecht |
| Wycombe | | 1 - 1 | | Bayern Munich |
| | | | | |
| 1 Mar 2011: Round 3, Leg 1
|
| AC Milan | | 1 - 0 | | Barcelona |
| AS Monaco | | 1 - 3 | | FC Schalke 04 |
| Anderlecht | | 1 - 0 | | Sporting Lisbon |
| Chievo | | 0 - 1 | | Feyenoord |
| Fenerbahce SK | | 2 - 2 | | PSV Eindhoven |
| Olympiakos | | 1 - 2 | | R. Madrid |
| Watford | | 2 - 4 | | Lyon |
| Wycombe | | 6 - 0 | | Chelsea |
| | | | | |
| 15 Mar 2011: Round 3, Leg 2
|
| Barcelona | | 1 - 0 | | AC Milan |
| | (1 - 1 agg.; 3 - 4 pen.) | |
| Chelsea | | 1 - 4 | | Wycombe |
| | (1 - 10 agg.) | |
| FC Schalke 04 | | 2 - 1 | | AS Monaco |
| | (5 - 2 agg.) | |
| Feyenoord | | 2 - 1 | | Chievo |
| | (3 - 1 agg.) | |
| Lyon | | 2 - 0 | | Watford |
| | (6 - 2 agg.) | |
| PSV Eindhoven | | 2 - 1 | | Fenerbahce SK |
| | (4 - 3 agg.) | |
| R. Madrid | | 1 - 0 | | Olympiakos |
| | (3 - 1 agg.) | |
| Sporting Lisbon | | 4 - 0 | | Anderlecht |
| | (4 - 1 agg.) | |
| | | | | |
| 29 Mar 2011: Quarter-Final, Leg 1
|
| AC Milan | | 0 - 0 | | Sporting Lisbon |
| Feyenoord | | 1 - 2 | | FC Schalke 04 |
| Lyon | | 1 - 4 | | Wycombe |
| R. Madrid | | 1 - 2 | | PSV Eindhoven |
| | | | | |
| 5 Apr 2011: Quarter-Final, Leg 2
|
| FC Schalke 04 | | 2 - 2 | | Feyenoord |
| | (4 - 3 agg.) | |
| PSV Eindhoven | | 2 - 2 | | R. Madrid |
| | (4 - 3 agg.) | |
| Sporting Lisbon | | 0 - 1 | | AC Milan |
| | (0 - 1 agg.) | |
| Wycombe | | 3 - 1 | | Lyon |
| | (7 - 2 agg.) | |
| | | | | |
| 26 Apr 2011: Semi-Final, Leg 1
|
| PSV Eindhoven | | 0 - 3 | | AC Milan |
| Wycombe | | 4 - 1 | | FC Schalke 04 |
| | | | | |
| 10 May 2011: Semi-Final, Leg 2
|
| AC Milan | | 1 - 0 | | PSV Eindhoven |
| | (4 - 0 agg.) | |
| FC Schalke 04 | | 0 - 3 | | Wycombe |
| | (1 - 7 agg.) | |
| | | | | |
| 25 May 2011: Final
|
| Wycombe | | vs. | | AC Milan |