| Matches Involving Wycombe |
| |
| 1 Aug 2010 | | (H) vs. Chelsea | W | 2 - 0 | Community Shield |
| 11 Aug 2010 | | (H) vs. West Brom | W | 2 - 0 | F.A. Premier League |
| 14 Aug 2010 | | (H) vs. Liverpool | W | 4 - 1 | F.A. Premier League |
| 20 Aug 2010 | | (A) vs. FC Schalke 04 | W | 1 - 2 | European Super Cup |
| 28 Aug 2010 | | (A) vs. Arsenal | W | 0 - 2 | F.A. Premier League |
| 4 Sep 2010 | | (H) vs. Newcastle | W | 4 - 1 | F.A. Premier League |
| 11 Sep 2010 | | (A) vs. Tottenham | W | 1 - 3 | F.A. Premier League |
| 14 Sep 2010 | | (A) vs. Hull City | W | 0 - 4 | League Cup - Round 2 |
| 18 Sep 2010 | | (H) vs. Reading | W | 3 - 1 | F.A. Premier League |
| 21 Sep 2010 | | (A) vs. Bayern Munich | W | 1 - 6 | ECC - Round 2 (Group Stage) |
| 25 Sep 2010 | | (A) vs. West Ham | W | 0 - 2 | F.A. Premier League |
| 28 Sep 2010 | | (H) vs. Fenerbahce SK | W | 4 - 2 | ECC - Round 2 (Group Stage) |
| 2 Oct 2010 | | (H) vs. Bolton | D | 1 - 1 | F.A. Premier League |
| 12 Oct 2010 | | (A) vs. Bournemouth | W | 1 - 6 | League Cup - Round 3 |
| 16 Oct 2010 | | (A) vs. Birmingham | W | 1 - 2 | F.A. Premier League |
| 23 Oct 2010 | | (H) vs. Middlesbrough | W | 4 - 1 | F.A. Premier League |
| 27 Oct 2010 | | (H) vs. Inter | W | 4 - 1 | ECC - Round 2 (Group Stage) |
| 30 Oct 2010 | | (A) vs. Blackburn | D | 1 - 1 | F.A. Premier League |
| 2 Nov 2010 | | (A) vs. Watford | W | 3 - 4 | League Cup - Round 4 |
| 6 Nov 2010 | | (H) vs. Manchester Utd | L | 0 - 1 | F.A. Premier League |
| 9 Nov 2010 | | (A) vs. Inter | W | 1 - 4 | ECC - Round 2 (Group Stage) |
| 13 Nov 2010 | | (A) vs. Chelsea | W | 1 - 4 | F.A. Premier League |
| 20 Nov 2010 | | (H) vs. Leeds United | D | 0 - 0 | F.A. Premier League |
| 27 Nov 2010 | | (A) vs. Wolverhampton | W | 0 - 5 | F.A. Premier League |
| 1 Dec 2010 | | (A) vs. Fenerbahce SK | W | 0 - 1 | ECC - Round 2 (Group Stage) |
| 4 Dec 2010 | | (H) vs. Manchester City | W | 3 - 1 | F.A. Premier League |
| 8 Dec 2010 | | (H) vs. Bayern Munich | D | 1 - 1 | ECC - Round 2 (Group Stage) |
| 11 Dec 2010 | | (A) vs. Watford | L | 1 - 0 | F.A. Premier League |
| 15 Dec 2010 | | (H) vs. Portsmouth | W | 5 - 0 | F.A. Premier League |
| 18 Dec 2010 | | (A) vs. Everton | W | 0 - 2 | F.A. Premier League |
| 21 Dec 2010 | | (H) vs. Brighton | W | 6 - 0 | League Cup - Quarter-Final |
| 25 Dec 2010 | | (A) vs. Liverpool | D | 2 - 2 | F.A. Premier League |
| 1 Jan 2011 | | (H) vs. Watford | W | 4 - 0 | F.A. Premier League |
| 5 Jan 2011 | | (A) vs. Manchester City | W | 1 - 5 | F.A. Premier League |
| 8 Jan 2011 | | (A) vs. Swansea City | W | 1 - 5 | English Cup - Round 3 |
| 11 Jan 2011 | | (H) vs. Manchester Utd | W | 5 - 1 | League Cup - Semi-Final, Leg 1 |
| 15 Jan 2011 | | (H) vs. Wolverhampton | W | 4 - 2 | F.A. Premier League |
| 18 Jan 2011 | | (A) vs. Manchester Utd | L | 3 - 1 | League Cup - Semi-Final, Leg 2 |
| 22 Jan 2011 | | (A) vs. Leeds United | W | 0 - 7 | F.A. Premier League |
| 27 Jan 2011 | | (H) vs. Chelsea | D | 2 - 2 | F.A. Premier League |
| 30 Jan 2011 | | (H) vs. Wigan Athletic | W | 6 - 2 | League Cup - Final |
| 2 Feb 2011 | | (A) vs. Manchester Utd | W | 1 - 3 | F.A. Premier League |
| 5 Feb 2011 | | (H) vs. Leicester City | W | 3 - 2 | English Cup - Round 4 |
| 12 Feb 2011 | | (H) vs. Blackburn | W | 3 - 0 | F.A. Premier League |
| 19 Feb 2011 | | (H) vs. Birmingham | W | 4 - 1 | F.A. Premier League |
| 23 Feb 2011 | | (A) vs. Portsmouth | W | 0 - 5 | F.A. Premier League |
| 26 Feb 2011 | | (H) vs. Sunderland | W | 4 - 0 | English Cup - Round 5 |
| 1 Mar 2011 | | (H) vs. Chelsea | W | 6 - 0 | ECC - Round 3, Leg 1 |
| 12 Mar 2011 | | (A) vs. West Brom | W | 1 - 6 | F.A. Premier League |
| 15 Mar 2011 | | (A) vs. Chelsea | W | 1 - 4 | ECC - Round 3, Leg 2 |
| 19 Mar 2011 | | (H) vs. Brighton | W | 4 - 0 | English Cup - Quarter-Final |
| 22 Mar 2011 | | (A) vs. Middlesbrough | W | 0 - 5 | F.A. Premier League |
| 26 Mar 2011 | | (A) vs. Bolton | W | 0 - 1 | F.A. Premier League |
| 29 Mar 2011 | | (A) vs. Lyon | W | 1 - 4 | ECC - Quarter-Final, Leg 1 |
| 2 Apr 2011 | | (H) vs. West Ham | W | 3 - 0 | F.A. Premier League |
| 5 Apr 2011 | | (H) vs. Lyon | W | 3 - 1 | ECC - Quarter-Final, Leg 2 |
| 10 Apr 2011 | | (H) vs. Crewe | W | 1 - 0 | English Cup - Semi-Final |
| 13 Apr 2011 | | (A) vs. Reading | W | 1 - 3 | F.A. Premier League |
| 16 Apr 2011 | | (H) vs. Tottenham | W | 2 - 0 | F.A. Premier League |
| 23 Apr 2011 | | (A) vs. Newcastle | W | 0 - 3 | F.A. Premier League |
| 26 Apr 2011 | | (H) vs. FC Schalke 04 | W | 4 - 1 | ECC - Semi-Final, Leg 1 |
| 30 Apr 2011 | | (H) vs. Arsenal | W | 5 - 3 | F.A. Premier League |
| 7 May 2011 | | (H) vs. Everton | W | 4 - 1 | F.A. Premier League |
| 10 May 2011 | | (A) vs. FC Schalke 04 | W | 0 - 3 | ECC - Semi-Final, Leg 2 |
| 21 May 2011 | | (A) vs. Watford | W | 1 - 2 | English Cup - Final |
| 25 May 2011 | | (H) vs. AC Milan | | | ECC - Final |