| Matches Involving Crystal Palace |
| |
| 1 Aug 2010 | | (H) vs. Manchester Utd | W | 2 - 1 | Community Shield |
| 11 Aug 2010 | | (H) vs. Nottm Forest | W | 1 - 0 | FA Premier League |
| 14 Aug 2010 | | (A) vs. West Ham | D | 2 - 2 | FA Premier League |
| 20 Aug 2010 | | (H) vs. Schaffhausen | W | 3 - 2 | European Super Cup |
| 28 Aug 2010 | | (H) vs. Newcastle | W | 2 - 1 | FA Premier League |
| 4 Sep 2010 | | (A) vs. Everton | W | 0 - 4 | FA Premier League |
| 11 Sep 2010 | | (H) vs. Sunderland | W | 4 - 1 | FA Premier League |
| 14 Sep 2010 | | (H) vs. Aston Villa | W | 4 - 2 | League Cup - Round 2 |
| 18 Sep 2010 | | (A) vs. Aston Villa | L | 2 - 1 | FA Premier League |
| 21 Sep 2010 | | (A) vs. Liebherr GAK | W | 2 - 4 | ECC - Round 2 (Group Stage) |
| 25 Sep 2010 | | (H) vs. Manchester Utd | W | 3 - 1 | FA Premier League |
| 28 Sep 2010 | | (H) vs. Sporting Lisbon | L | 0 - 1 | ECC - Round 2 (Group Stage) |
| 2 Oct 2010 | | (A) vs. Liverpool | L | 3 - 2 | FA Premier League |
| 9 Oct 2010 | | (H) vs. Fulham | L | 1 - 2 | FA Premier League |
| 12 Oct 2010 | | (A) vs. Tottenham | W | 1 - 3 | League Cup - Round 3 |
| 16 Oct 2010 | | (A) vs. Bolton | W | 1 - 2 | FA Premier League |
| 23 Oct 2010 | | (H) vs. Preston | W | 4 - 3 | FA Premier League |
| 27 Oct 2010 | | (H) vs. Molde | W | 4 - 1 | ECC - Round 2 (Group Stage) |
| 30 Oct 2010 | | (A) vs. Blackburn | D | 2 - 2 | FA Premier League |
| 2 Nov 2010 | | (A) vs. Bolton | W | 0 - 4 | League Cup - Round 4 |
| 6 Nov 2010 | | (H) vs. Birmingham | W | 3 - 1 | FA Premier League |
| 9 Nov 2010 | | (A) vs. Molde | D | 2 - 2 | ECC - Round 2 (Group Stage) |
| 13 Nov 2010 | | (A) vs. Manchester City | W | 1 - 3 | FA Premier League |
| 20 Nov 2010 | | (A) vs. Portsmouth | W | 1 - 4 | FA Premier League |
| 27 Nov 2010 | | (H) vs. Ipswich Town | D | 2 - 2 | FA Premier League |
| 1 Dec 2010 | | (A) vs. Sporting Lisbon | W | 1 - 3 | ECC - Round 2 (Group Stage) |
| 4 Dec 2010 | | (A) vs. Southampton | L | 3 - 1 | FA Premier League |
| 8 Dec 2010 | | (H) vs. Liebherr GAK | W | 2 - 1 | ECC - Round 2 (Group Stage) |
| 11 Dec 2010 | | (H) vs. Arsenal | W | 2 - 1 | FA Premier League |
| 18 Dec 2010 | | (A) vs. Chelsea | W | 1 - 3 | FA Premier League |
| 21 Dec 2010 | | (A) vs. Reading | W | 2 - 3 | League Cup - Quarter-Final |
| 25 Dec 2010 | | (H) vs. West Ham | W | 5 - 2 | FA Premier League |
| 29 Dec 2010 | | (A) vs. Manchester Utd | W | 1 - 2 | FA Premier League |
| 1 Jan 2011 | | (H) vs. Chelsea | W | 2 - 1 | FA Premier League |
| 5 Jan 2011 | | (H) vs. Liverpool | W | 4 - 2 | FA Premier League |
| 8 Jan 2011 | | (A) vs. Tranmere Rovers | L | 3 - 2 | English Cup - Round 3 |
| 11 Jan 2011 | | (A) vs. Cardiff City | L | 2 - 1 | League Cup - Semi-Final, Leg 1 |
| 15 Jan 2011 | | (A) vs. Newcastle | W | 1 - 3 | FA Premier League |
| 18 Jan 2011 | | (H) vs. Cardiff City | D | 2 - 2 | League Cup - Semi-Final, Leg 2 |
| 22 Jan 2011 | | (H) vs. Everton | D | 3 - 3 | FA Premier League |
| 26 Jan 2011 | | (A) vs. Preston | W | 2 - 3 | FA Premier League |
| 2 Feb 2011 | | (H) vs. Bolton | W | 4 - 1 | FA Premier League |
| 5 Feb 2011 | | (A) vs. Ipswich Town | W | 1 - 3 | FA Premier League |
| 9 Feb 2011 | | (A) vs. Nottm Forest | L | 1 - 0 | FA Premier League |
| 12 Feb 2011 | | (A) vs. Sunderland | W | 1 - 2 | FA Premier League |
| 19 Feb 2011 | | (H) vs. Portsmouth | L | 2 - 3 | FA Premier League |
| 1 Mar 2011 | | (H) vs. Juventus | W | 4 - 2 | ECC - Round 3, Leg 1 |
| 5 Mar 2011 | | (H) vs. Manchester City | L | 1 - 2 | FA Premier League |
| 12 Mar 2011 | | (H) vs. Aston Villa | W | 4 - 2 | FA Premier League |
| 15 Mar 2011 | | (A) vs. Juventus | D | 1 - 1 | ECC - Round 3, Leg 2 |
| 29 Mar 2011 | | (H) vs. Barcelona | D | 3 - 3 | ECC - Quarter-Final, Leg 1 |
| 5 Apr 2011 | | (A) vs. Barcelona | W | 2 - 3 | ECC - Quarter-Final, Leg 2 |
| 13 Apr 2011 | | (A) vs. Fulham | L | 1 - 0 | FA Premier League |
| 16 Apr 2011 | | (H) vs. Southampton | W | 2 - 0 | FA Premier League |
| 20 Apr 2011 | | (H) vs. Blackburn | W | 2 - 1 | FA Premier League |
| 26 Apr 2011 | | (A) vs. Celtic | L | 2 - 1 | ECC - Semi-Final, Leg 1 |
| 30 Apr 2011 | | (A) vs. Arsenal | D | 2 - 2 | FA Premier League |
| 4 May 2011 | | (A) vs. Birmingham | W | 1 - 3 | FA Premier League |
| 10 May 2011 | | (H) vs. Celtic | W | 2 - 1 | ECC - Semi-Final, Leg 2 |
| 25 May 2011 | | (A) vs. Real Madrid | | | ECC - Final |